The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2018

Filed:

Nov. 04, 2015
Applicant:

Case Western Reserve University, Cleveland, OH (US);

Inventors:

Nicole Seiberlich, Shaker Heights, OH (US);

Jesse Hamilton, Cleveland, OH (US);

Mark Griswold, Shaker Heights, OH (US);

Assignee:

Case Western Reserve University, Cleveland, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01R 33/50 (2006.01); G01R 33/483 (2006.01); G01R 33/56 (2006.01); G01R 33/561 (2006.01);
U.S. Cl.
CPC ...
G01R 33/50 (2013.01); G01R 33/483 (2013.01); G01R 33/5602 (2013.01); G01R 33/5613 (2013.01);
Abstract

Example embodiments associated with characterizing a sample using NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals and a characterization logic that characterizes a tissue in the object as a result of comparing acquired signals to reference signals. Example embodiments facilitate analyzing voxels having multiple compartments that may experience magnetic exchange. The compartments may be, for example, an intracellular volume and an extracellular volume in a tissue that experiences magnetic exchange due to the movement of water between the volumes.


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