The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2018

Filed:

Apr. 05, 2013
Applicant:

Quidel Cardiovascular Inc., San Diego, CA (US);

Inventors:

William Patrick Coffey, Encinitas, CA (US);

Paul Michael Crivelli, San Diego, CA (US);

Austin Matthew Derfus, Carlsbad, CA (US);

Tuan Hoang Do, San Diego, CA (US);

Remus Anders Brix Haupt, Encinitas, CA (US);

Emily Parker, Encinitas, CA (US);

Gregory Reneff, San Diego, CA (US);

Armando Raul Tovar, San Diego, CA (US);

Assignee:

Quidel Cardiovascular Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54306 (2013.01); G01N 33/54366 (2013.01); B01L 2200/0621 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0874 (2013.01); B01L 2300/0883 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0688 (2013.01);
Abstract

A combination of capillary forces and gas pressure is used to control the movement of liquid samples within a microfluidic device. A liquid sample introduced to a proximal portion of a capillary channel of a microfluidic device moves by capillary action partway along the capillary channel. As the liquid sample moves, a pressure of a gas acting upon a distal gas-liquid interface of the liquid sample increases by an amount sufficient to stop further movement of the liquid sample. To initiate further movement of the liquid sample, a pump connected to a distal portion of the capillary channel decreases the pressure of the gas acting upon the distal gas-liquid interface of the liquid sample by an amount sufficient to permit the liquid sample to move by capillary action further along the capillary channel of the microfluidic device.


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