The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2018
Filed:
Dec. 16, 2016
Sanofi Pasteur, Lyons, FR;
Jérome Le Hir, Toulouse, FR;
Pascal Loubiere, Donneville, FR;
Fabien Barbirato, Brignais, FR;
Nicholas Lindley, Parisot, FR;
Sanofi Pasteur, Lyons, FR;
Abstract
The invention concerns a method for producing, on an industrial scale, capsular polysaccharide oftype b (PRP) intended for vaccine purposes, according to which a strain oftype b (Hib) is cultured in a culture medium, the culture supernatant is harvested and treated in order to extract the capsular polysaccharide therefrom, said culture medium comprising at least: —one source of carbon, —protoporphyrin, —salts, —amino acids, —NAD or NADH, —vitamins, —means for regulating the pH, characterized in that said culture medium is chemically defined.