The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2018
Filed:
Jun. 05, 2015
Board of Trustees of Michigan State University, East Lansing, MI (US);
Fredric P. Manfredsson, Grand Rapids, MI (US);
Jack W. Lipton, Grand Rapids, MI (US);
Nicholas Kanaan, Grand Rapids, MI (US);
Timothy Collier, Grand Rapids, MI (US);
Kathy Steece-Collier, Grand Rapids, MI (US);
Caryl E. Sortwell, Grand Rapids, MI (US);
Board of Trustees of Michigan State University, East Lansing, MI (US);
Abstract
Methods of treating movement disorders by reducing the activity of Nurr1 are disclosed. These methods are particularly applicable to subjects suffering from Parkinson's disease who have either developed levodopa-induced dyskinesia (LID) or are at risk of developing LID. In some aspects, the invention relates to a method for treating a movement disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a composition, wherein said composition reduces the activity of a nuclea receptor related 1 protein ('Nurr1'). In some embodiments, the movement disorder is a dyskinesia. The movement disorder may be a levodopa-induced dyskinesia.