The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2018

Filed:

May. 12, 2015
Applicants:

Inserm (Institut National DE LA Santé ET DE LA Recherche Médicale), Paris, FR;

Centre Hospitalier Universitaire DE Toulouse, Toulouse, FR;

Institut Claudius Regaud, Toulouse, FR;

Université Pauls Sabatier Toulouse Iii, Toulouse, FR;

Inventors:

Bruno Segui, Toulouse, FR;

Nathalie Andrieu-Abadie, Toulouse, FR;

Thierry Levade, Toulouse, FR;

Celine Colacios Viatge, Toulouse, FR;

Philippe Rochaix, Toulouse, FR;

Florie Bertrand, Toulouse, FR;

Herve Benoist, Toulouse, FR;

Julia Rochotte, Toulouse, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 39/00 (2006.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C07K 14/715 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7151 (2013.01); A61K 38/1793 (2013.01); C07K 16/241 (2013.01); C07K 16/2878 (2013.01); C07K 16/3053 (2013.01); G01N 33/5743 (2013.01); A61K 2039/505 (2013.01); A61K 2039/55 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/76 (2013.01); C07K 2319/30 (2013.01); G01N 2333/525 (2013.01); G01N 2333/70539 (2013.01);
Abstract

The present invention relates to a TNFα blocking agent for use in the treatment and prevention of melanoma in a subject in whom melanoma cells express MHCI and in whom stroma cells exhibit TNF expression.


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