The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2018

Filed:

Sep. 22, 2015
Applicant:

Glaxosmithkline Intellectual Property Development Limited, Brentford, Middlesex, GB;

Inventors:

Niall Andrew Anderson, Stevenage, GB;

Ian Baxter Campbell, Stevenage, GB;

Matthew Howard James Campbell-Crawford, Stevenage, GB;

Ashley Paul Hancock, Stevenage, GB;

Seble Lemma, Stevenage, GB;

Simon John Fawcett MacDonald, Stevenage, GB;

John Martin Pritchard, Stevenage, GB;

Panayiotis Alexandrou Procopiou, Stevenage, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07B 59/00 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07B 59/002 (2013.01); C07B 2200/05 (2013.01);
Abstract

A compound of formula (I) or a salt thereof: wherein Rrepresents a five-membered aromatic heterocycle selected from a N- or a C-linked mono- or di-substituted pyrazole, an N- or a C-linked optionally mono- or di-substituted triazole or an N- or a C-linked optionally mono- or di-substituted imidazole, which five-membered aromatic heterocycle may be substituted by one or two of the groups selected a methyl group, an ethyl group, a fluorine atom, a hydroxymethyl group, a 2-hydroxypropan-2-yl group, a trifluoromethyl group, a difluoromethyl group or a fluoromethyl group, except that when Rrepresents an N-linked mono- or di-substituted pyrazole, Rdoes not represent 3,5-Dimethyl-1H-pyrazol-1-yl, 5-Methyl-1H-pyrazol-1-yl, 5-Ethyl-3-methyl-1H-pyrazol-1-yl, 3,5-Diethyl-1H-pyrazol-1-yl, 4-Fluoro-3,5-dimethyl-1H-pyrazol-1-yl, 3-Methyl-1H-pyrazol-1-yl or 1H-pyrazol-1-yl.


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