The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2018

Filed:

Sep. 15, 2014
Applicant:

Emergent Virology Llc, Gaithersburg, MD (US);

Inventors:

Urban Ramstedt, Bethesda, MD (US);

Raju Penmasta, Herndon, VA (US);

Hitesh Batra, Herndon, VA (US);

Tam Nguyen, Gaithersburg, MD (US);

Assignee:

Emergent Virology LLC, Gaithersburg, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/06 (2006.01); C07D 211/46 (2006.01); C07D 211/40 (2006.01);
U.S. Cl.
CPC ...
C07D 405/06 (2013.01); C07D 211/40 (2013.01); C07D 211/46 (2013.01);
Abstract

The present application provide novel iminosugars and their use in treatment of viral infections, such as Dengue infection and Influenza A infection. The present inventors discovered certain deoxynojirimycin derivatives may be effective against one or more viruses, which may be, for example, a Dengue virus and/or a virus belonging to the Orthomyxoviridae family, such as an Influenza A virus. In particular, such deoxynojirimycin derivatives may be useful for treating a disease or condition caused by or associated with one or more viruses. In certain embodiments, the deoxynojirimycin derivatives may increase a survival rate or probability for a subject infected with one or more viruses, which may be, for example, a Dengue virus and/or a virus belonging to the Orthomyxoviridae family, such as an Influenza A virus.


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