The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2018

Filed:

Aug. 04, 2015
Applicant:

Vitae Pharmaceuticals, Inc., Fort Washington, PA (US);

Inventors:

David A. Claremon, Maple Glen, PA (US);

Chengguo Dong, Staten Island, NY (US);

Yi Fan, Doylestown, PA (US);

Katerina Leftheris, San Diego, CA (US);

Stephen D. Lotesta, Burlington, NJ (US);

Suresh B. Singh, Kendall Park, NJ (US);

Colin M. Tice, Maple Glen, PA (US);

Wei Zhao, North Potomac, MD (US);

Yajun Zheng, Hockessin, DE (US);

Linghang Zhuang, Chalfont, PA (US);

Assignee:

Vitae Pharmaceuticals, Inc., Madison, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 241/04 (2006.01); C07D 403/04 (2006.01); C07D 413/14 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 403/14 (2006.01); C07D 405/06 (2006.01); C07D 413/04 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 497/04 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 241/04 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 405/06 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01); C07D 497/04 (2013.01); C07D 513/04 (2013.01);
Abstract

Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are liver X receptor modulators, and which are useful in the treatment of diseases and disorders associated with the liver X receptor. Also provided are the compounds of Formula (I) and pharmaceutical compositions thereof for treating atherosclerosis, cardiovascular disease, Alzheimer's disease, dermatitis, dyslipidemia, cancer and other diseases or disorders.


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