The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2018
Filed:
May. 10, 2016
Applicant:
Piramal Enterprises Limited, Mumbai, IN;
Inventors:
Dhileep Kumar Krishnamurthy, Maharashtra, IN;
Milind Gharpure, Maharashtra, IN;
Narender Rao Somisetti, Telengana State, IN;
Murali Rajappa, Telengana State, IN;
Rajshekar Aareddy, Telengana State, IN;
Damodhar Kasireddy, Telengana State, IN;
Assignee:
PIRAMAL ENTERPRISES LIMITED, Mumbai, IN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 253/30 (2006.01); C07C 213/08 (2006.01); C07C 217/60 (2006.01); C07C 255/42 (2006.01); B01J 31/02 (2006.01); C07B 63/00 (2006.01);
U.S. Cl.
CPC ...
C07C 253/30 (2013.01); B01J 31/0239 (2013.01); C07B 63/00 (2013.01); C07C 213/08 (2013.01); C07C 217/60 (2013.01); C07C 255/42 (2013.01); C07C 2531/02 (2013.01);
Abstract
A process for the preparation of 5-(3,4-dimethoxyphenylethyl) methyl-amino-2-(3,4-dimethoxyphenyl)-2-isopropyl valeronitrile, which is known as Verapamil is described. A process for improving the purity of verapamil and therefore of its hydrochloride represented as the compound of formula I, by efficient removal of the impurities formed, affording a product of purity greater than 99% is described.