The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2018
Filed:
Mar. 01, 2017
Applicant:
Bristol-myers Squibb Company, Princeton, NJ (US);
Inventors:
Martin Patrick Allen, Flemington, NJ (US);
Eric P. Gillis, Cheshire, CT (US);
David R. Langley, Meriden, CT (US);
Michael Matthew Miller, Lambertville, NJ (US);
Eric Mull, Guilford, CT (US);
Li-Qiang Sun, Glastonbury, CT (US);
Kap-Sun Yeung, Madison, CT (US);
Katharine A. Grant-Young, Madison, CT (US);
Nicholas A. Meanwell, East Hampton, CT (US);
Paul Michael Scola, Glastonbury, CT (US);
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/39 (2006.01); A61K 45/06 (2006.01); C07K 7/08 (2006.01); C07K 7/56 (2006.01); G01N 33/574 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 45/06 (2013.01); C07K 7/08 (2013.01); C07K 7/56 (2013.01); G01N 33/574 (2013.01); A61K 2039/55516 (2013.01);
Abstract
The present disclosure provides novel macrocyclic compounds which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.