The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2018
Filed:
Nov. 13, 2014
Applicant:
Epizyme, Inc., Cambridge, MA (US);
Inventors:
Roy M. Pollock, Medford, MA (US);
Scott R. Daigle, Newburyport, MA (US);
Eric Hedrick, Summit, NJ (US);
Nigel Waters, Belmont, MA (US);
Blythe Thomson, Newton, MA (US);
Assignee:
Epizyme, Inc., Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7076 (2006.01); C07H 19/16 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7076 (2013.01); C07H 19/16 (2013.01);
Abstract
The present invention relates to DOT1L inhibitors. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating disorders in which DOT1-mediated protein methylation plays a part, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.