The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2018
Filed:
Sep. 23, 2015
Applicants:
University of Massachusetts, Boston, MA (US);
University of Miami, Miami, FL (US);
Inventors:
Edward I. Ginns, Shrewsbury, MA (US);
Marzena Galdzicka, Shrewsbury, MA (US);
Janice A. Egeland, Hershey, PA (US);
Assignees:
University of Massachusetts, Boston, MA (US);
University of Miami, Miami, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4418 (2006.01); A61K 31/05 (2006.01); C12Q 1/6883 (2018.01);
U.S. Cl.
CPC ...
A61K 31/4418 (2013.01); A61K 31/05 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/166 (2013.01);
Abstract
Methods for treating and diagnosing psychiatric affective disorders, e.g., an affective disorder associated with aberrant Sonic Hedgehog (Shh) signaling, by administering to the subject a therapeutically effective amount of an antagonist to Smoothened (Smo), an antagonist to Patched-1 (Ptch-1) and/or an antagonist to Shh.