The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2018

Filed:

May. 21, 2015
Applicant:

Vivex Biomedical, Inc., Marietta, GA (US);

Inventor:

Theodore I. Malinin, Key Biscayne, FL (US);

Assignee:

Vivex Biomedical, Inc., Atlanta, GA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 2/44 (2006.01); A61L 27/36 (2006.01); A61F 2/30 (2006.01);
U.S. Cl.
CPC ...
A61F 2/442 (2013.01); A61L 27/3608 (2013.01); A61L 27/3658 (2013.01); A61L 27/3683 (2013.01); A61F 2002/30754 (2013.01); A61F 2002/4445 (2013.01); A61L 2400/06 (2013.01); A61L 2430/38 (2013.01);
Abstract

A particulate composition for stimulating nucleus pulposus regeneration has a particulate composition made of vertebral end-plates having an osseous component wherein the composition is milled, ground or particulized into particles from 10 to 1000 microns in size. At least a part of the composition can be non-demineralized or demineralized or a mixture of demineralized and non-demineralized particles from the vertebral end-plates. Preferably, the non-demineralized part is not subjected to harsh chemical treating. To possibly enhance the release of growth factors and other similar substances from the osseous layer of the end-plate, the material may be treated with hydrochloric acid, ethylene diamine or other demineralizing agents or regimens.


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