The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

Oct. 20, 2016
Applicant:

Olympus Corporation, Tokyo, JP;

Inventors:

Taro Hayashi, Tachikawa, JP;

Isao Sakane, Hachioji, JP;

Yoko Ohashi, Tokyo, JP;

Assignee:

OLYMPUS CORPORATION, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6897 (2018.01); C12N 5/077 (2010.01); G01N 21/64 (2006.01); G01N 33/483 (2006.01); G06K 9/00 (2006.01); G06T 7/00 (2017.01); G06T 7/20 (2017.01);
U.S. Cl.
CPC ...
C12Q 1/6897 (2013.01); C12N 5/0657 (2013.01); G01N 21/6486 (2013.01); G01N 33/4833 (2013.01); G06K 9/00134 (2013.01); G06T 7/0012 (2013.01); G06T 7/0022 (2013.01); G06T 7/20 (2013.01); G06T 7/97 (2017.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01); C12N 2510/00 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/10064 (2013.01); G06T 2207/30048 (2013.01);
Abstract

A method for monitoring differentiation into cardiac muscle cells includes keeping, in an alive state, cells into which a reporter gene of luminescent protein configured to vary in luminescence intensity according to an expression of myocardial differentiation marker gene is introduced. The method includes acquiring a luminescence image as a still image by imaging light emitted from the cells in a light shielding state. The method includes acquiring sequential images with illuminating the cells. The method includes associating biological information obtained from the sequential images with biological information obtained from the still image.


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