The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

Sep. 03, 2015
Applicant:

Pacific Biosciences of California, Inc., Menlo Park, CA (US);

Inventors:

Adrian Fehr, San Francisco, CA (US);

Nathaniel Joseph McCaffrey, Mill Valley, CA (US);

Stephen Turner, Seattle, WA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6874 (2018.01); B01L 3/00 (2006.01); G01N 21/64 (2006.01); G01N 21/75 (2006.01); B82Y 20/00 (2011.01); G01N 33/543 (2006.01); G02B 6/122 (2006.01); G01N 21/03 (2006.01); G01N 21/05 (2006.01); G01N 21/77 (2006.01); C12Q 1/6825 (2018.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); B01L 3/502707 (2013.01); B01L 3/502715 (2013.01); B82Y 20/00 (2013.01); C12Q 1/6825 (2013.01); C12Q 1/6869 (2013.01); G01N 21/03 (2013.01); G01N 21/0303 (2013.01); G01N 21/05 (2013.01); G01N 21/64 (2013.01); G01N 21/645 (2013.01); G01N 21/648 (2013.01); G01N 21/6428 (2013.01); G01N 21/6452 (2013.01); G01N 21/6456 (2013.01); G01N 21/75 (2013.01); G01N 21/77 (2013.01); G01N 33/54373 (2013.01); G02B 6/1226 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/168 (2013.01); G01N 2021/0346 (2013.01); G01N 2021/6434 (2013.01); G01N 2021/6439 (2013.01); G01N 2021/6441 (2013.01); G01N 2021/6463 (2013.01); G01N 2021/757 (2013.01); G01N 2021/7786 (2013.01); G01N 2201/067 (2013.01); G01N 2201/068 (2013.01); G01N 2201/08 (2013.01); Y10T 436/143333 (2015.01);
Abstract

An analytical device including an optically opaque cladding, a sequencing layer including a substrate disposed below the cladding, and a waveguide assembly for receiving optical illumination and introducing illumination into the device. The illumination may be received from a top, a side edge, and a bottom of the device. The waveguide assembly may include a nanoscale aperture disposed in the substrate and extending through the cladding. The aperture defines a reaction cell for receiving a set of reactants. In various aspects, the device includes a sensor element and the illumination pathway is through the sensor element. Waveguides and illumination devices, such as plasmonic illumination devices, are also disclosed. Methods for forming and operating the devices are also disclosed.


Find Patent Forward Citations

Loading…