The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

Mar. 13, 2014
Applicant:

Modernatx, Inc., Cambridge, MA (US);

Inventors:

Stephane Bancel, Cambridge, MA (US);

William Joseph Issa, Roslindale, MA (US);

John Grant Aunins, Cambridge, MA (US);

Tirtha Chakraborty, Medford, MA (US);

Assignee:

ModernaTX, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); C12Q 1/68 (2018.01); C12N 15/10 (2006.01); C12Q 1/6865 (2018.01);
U.S. Cl.
CPC ...
C12P 19/34 (2013.01); C12N 15/101 (2013.01); C12Q 1/6865 (2013.01);
Abstract

Described are methods for production of RNA transcripts using a non-amplified, linearized DNA template in an in vitro transcription reaction. Enzymatic 5' capping and oligo dT purification can also be included in the methods.


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