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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10138466 B1

PDFFull Text
Date of Patent:
Nov. 27, 2018

Filed:

Sep. 15, 2017

Compositions and methods for differentiating stem cells into cell populations comprising beta-like cells

Applicant:

Regenerative Medical Solutions, Inc., Park Ridge, IL (US);

Inventors:

Xiaofang Xu, Park Ridge, IL (US);

Jon Odorico, Park Ridge, IL (US);

Erik Forsberg, Park Ridge, IL (US);

Amber A. Mael, Madison, WI (US);

Assignee:

REGENERATIVE MEDICAL SOLUTIONS, INC., Park Ridge, IL (US);

Attorneys:

Casimir Jones, S.C.

Tanya A. Arenson

Primary Examiner:

Thaian N Ton

Int. Cl.
CPC ...
C12N 5/071 (2010.01); A61K 35/39 (2015.01); A61K 9/16 (2006.01); A61K 45/06 (2006.01); A61K 9/50 (2006.01); G01N 33/50 (2006.01); A61K 35/545 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0676 (2013.01); A61K 9/1652 (2013.01); A61K 9/5036 (2013.01); A61K 35/39 (2013.01); A61K 45/06 (2013.01); G01N 33/507 (2013.01); H05K 999/99 (2013.01); A61K 35/545 (2013.01); C12N 2500/05 (2013.01); C12N 2500/22 (2013.01); C12N 2500/25 (2013.01); C12N 2500/38 (2013.01); C12N 2500/44 (2013.01); C12N 2500/90 (2013.01); C12N 2501/01 (2013.01); C12N 2501/105 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2501/117 (2013.01); C12N 2501/155 (2013.01); C12N 2501/16 (2013.01); C12N 2501/33 (2013.01); C12N 2501/335 (2013.01); C12N 2501/385 (2013.01); C12N 2501/395 (2013.01); C12N 2501/40 (2013.01); C12N 2501/727 (2013.01); C12N 2501/91 (2013.01); C12N 2501/998 (2013.01); C12N 2501/999 (2013.01); C12N 2506/02 (2013.01); C12N 2506/45 (2013.01);
Abstract

Methods, kits, compositions, and systems are provided for culturing pluripotent stem cells to produce populations of cells comprising beta-like cells (e.g., pancreatic lineage, glucose-responsive, and/or insulin-producing). In particular, culture conditions are provided that result in the generation of beta-like cells from a starting culture of human pluripotent stem cells.

Find Patent Forward Citations

Xu, Xiaofang. (2018). Compositions and methods for differentiating stem cells into cell populations comprising beta-like cells (U.S. Patent No. 10138466). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10138466

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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