The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2018
Filed:
Oct. 05, 2011
Applicant:
Jarno Robin, Skovlunde, DK;
Inventor:
Jarno Robin, Skovlunde, DK;
Assignee:
Novo Nordisk Healthcare AG, Zurich, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/755 (2006.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
C07K 14/755 (2013.01); C12N 9/644 (2013.01); C12N 9/6424 (2013.01); C12N 9/6437 (2013.01);
Abstract
The present invention relates to a process for the production of a haemostasis protein by continuous perfusion culturing of a cell culture in suspension, said cell culture expressing said haemostasis protein into said culture suspension, wherein the cell culture flows across a filter module, which filter module leads to a harvest port, the filter module having a mesh size of from 0.1 to 2.9 μm allowing passage across of the haemostasis protein and wherein the flow across the filter module is an alternating tangential flow. The invention also relates to a protein produced by the process of the invention.