The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

Jun. 03, 2016
Applicant:

Euroimmun Medizinische Labordiagnostika Ag, Luebeck, DE;

Inventors:

Winfried Stoecker, Gross Groenau, DE;

Lars Komorowski, Ratzeburg, DE;

Madeleine Scharf, Luebeck, DE;

Ramona Miske, Luebeck, DE;

Yvonne Denno, Luebeck, DE;

Inga-Madeleine Dettmann, Ahrensboek, DE;

Christian Probst, Ratzeburg, DE;

Stefanie Hahn, Reinfeld, DE;

Stephanie Kade, Wismar, DE;

George Trendelenburg, Goettingen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); C07K 14/00 (2006.01); C07K 14/47 (2006.01); G01N 33/564 (2006.01); G01N 33/68 (2006.01); C07K 16/28 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/705 (2013.01); C07K 14/00 (2013.01); C07K 14/4713 (2013.01); C07K 16/28 (2013.01); G01N 33/564 (2013.01); G01N 33/6854 (2013.01); G01N 33/6893 (2013.01); G01N 33/6896 (2013.01); A61K 38/00 (2013.01); C07B 2200/11 (2013.01); C07K 2317/20 (2013.01); G01N 2333/47 (2013.01); G01N 2800/16 (2013.01); G01N 2800/28 (2013.01); G01N 2800/285 (2013.01); G01N 2800/7095 (2013.01);
Abstract

A method for diagnosing a disease by detecting an autoantibody that binds to flotillin1 and/or flotillin2 in a sample, a polypeptide comprising flotillin1 and/or flotillin2 or a variant thereof, which may be immobilized, a method of treating a disease by applying to a subject the polypeptide that binds to an autoantibody, an autoantibody binding to flotillin1 and/or flotillin2, a method for isolating the autoantibody, a pharmaceutical composition, a medical device and test kit comprising the polypeptide, are provided. A method for detecting the presence of an autoantibody is also provided.


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