The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2018
Filed:
Jul. 03, 2015
Paris Sciences ET Lettres -quartier Latin, Paris, FR;
Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;
Universite Pierre ET Marie Curie—paris 6 (Upmc), Paris, FR;
Arnaud Gautier, Paris, FR;
Ludovic Jullien, Arcueil, FR;
PARIS SCIENCES ET LETTRES—QUARTIER LATIN, Paris, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS), Paris, FR;
UNIVERSITE PIERRE ET MARIE CURIE—PARIS 6 (UPMC), Paris, FR;
Abstract
Disclosed is a functional derivative of a Photoactive Yellow Protein (PYP), or a functional fragment thereof, for fluorescently labelling particles, e.g. proteins, or surfaces, which is capable of binding reversibly a fluorogenic chromophore of formula (I), and which is capable of enhancing the brightness of the fluorogenic chromophore upon complexation thereto; and of inducing the spectral shift of the fluorogenic chromophore through the ionization of an auxochromic group thereof.