The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

Jun. 17, 2016
Applicant:

Nitto Denko Corporation, Ibaraki-shi, Osaka, JP;

Inventors:

Shohei Horie, Ibaraki, JP;

Tatsuya Konishi, Ibaraki, JP;

Kenjiro Mori, Ibaraki, JP;

Eri Maeta, Ibaraki, JP;

Tsuyoshi Mukobata, Ibaraki, JP;

Masafumi Iwamoto, Ibaraki, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C07H 21/02 (2006.01); C12Q 1/6806 (2018.01); C12N 15/10 (2006.01); C07H 1/06 (2006.01);
U.S. Cl.
CPC ...
C07H 21/02 (2013.01); C07H 1/06 (2013.01); C12N 15/1006 (2013.01); C12Q 1/6806 (2013.01);
Abstract

The invention provides a cut-out method capable of suppressing production of a byproduct, wherein the object RNA oligonucleotide is not cleaved from a universal linker, which is produced in cutting out the object RNA oligonucleotide from the universal support, and capable of increasing the yield of the object RNA oligonucleotide. The RNA oligonucleotide cut-out method includes a step of bringing a universal support supporting an RNA oligonucleotide in contact with an aqueous solution containing alkylamine and a monovalent inorganic salt.


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