The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

Mar. 06, 2015
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Msd R&d (China) Co., Ltd., Shanghai, CN;

Inventors:

Peter D. Williams, Harleysville, PA (US);

John A. McCauley, Maple Glen, PA (US);

Christopher J. Bungard, Lansdale, PA (US);

David Jonathan Bennett, Winchester, MA (US);

Sherman T. Waddell, Westfield, NJ (US);

Gregori J. Morriello, Randolph, NJ (US);

Lehua Chang, Ramsey, NJ (US);

Michael P. Dwyer, Scotch Plains, NJ (US);

M. Katharine Holloway, Lansdale, PA (US);

Alejandro Crespo, Edison, NJ (US);

Xin-Jie Chu, Shanghai, CN;

Catherine Wiscount, Allentown, PA (US);

H. Marie Loughran, Perkasie, PA (US);

Jesse J. Manikowski, Norristown, PA (US);

Jurgen Schulz, Motherwell, GB;

Kartik M. Keertikar, East Windsor, NJ (US);

Bin Hu, Shanghai, CN;

Bin Zhong, Shanghai, CN;

Tao Ji, Shanghai, CN;

Assignees:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

MSD R&D (China) Co., Ltd., Shanghai, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/554 (2006.01); C07D 513/08 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 513/08 (2013.01); A61K 31/554 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention is directed to compounds of Formula I pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.


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