The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

Sep. 06, 2017
Applicant:

Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;

Inventors:

Pingrong Liu, Southbury, CT (US);

Craig Andrew Miller, New Milford, CT (US);

Maolin Yu, Brookfield, CT (US);

Zhonghua Zhang, Ridgefield, CT (US);

Sabine Ruppel, New Milford, CT (US);

Anil K. Padyana, Lexington, MA (US);

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/166 (2006.01); C07C 237/38 (2006.01); C07D 471/04 (2006.01); C07D 401/04 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 487/04 (2006.01); C07D 231/12 (2006.01); C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 231/12 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention relates to compounds of formula (I): or pharmaceutically acceptable salts thereof, wherein R, R, X, Y, and HET are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.


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