The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

May. 23, 2017
Applicants:

Abbvie S.à.r.l., Luxembourg, LU;

Galapagos NV, Mechelen, BE;

Inventors:

Robert J. Altenbach, Chicago, IL (US);

Andrew Bogdan, Evanston, IL (US);

Ghjuvanni Petru Diunisu Coti, Mechelen, BE;

Marlon D. Cowart, Round Lake Bach, IL (US);

Stephen N Greszler, Vernon Hills, IL (US);

Hans Kelgtermans, Mechelen, BE;

Philip R Kym, Libertyville, IL (US);

Steven Emiel Van der Plas, Mechelen, BE;

Xueqing Wang, Northbrook, IL (US);

Assignees:

AbbVie S.á.r.l., Luxembourg, LU;

Galapagos NV, Mechelen, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); C07D 417/04 (2006.01); C07D 413/14 (2006.01); A61K 45/06 (2006.01); A61K 31/444 (2006.01); C07D 417/14 (2006.01); A61K 31/4439 (2006.01);
U.S. Cl.
CPC ...
C07D 413/04 (2013.01); A61K 31/444 (2013.01); A61K 31/4439 (2013.01); A61K 45/06 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01);
Abstract

The invention discloses compounds of Formula I, wherein X, X, R, and Rare as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention.


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