The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

Apr. 27, 2015
Applicant:

Avedro, Inc., Waltham, MA (US);

Inventors:

Marc D. Friedman, Needham, MA (US);

Pavel Kamaev, Lexington, MA (US);

David Muller, Boston, MA (US);

Radha Pertaub, Watertown, MA (US);

Ronald Scharf, Waltham, MA (US);

Evan Sherr, Ashland, MA (US);

David Usher, Waltham, MA (US);

Assignee:

Avedro, Inc., Waltham, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61M 5/00 (2006.01); A61B 3/10 (2006.01); A61N 5/06 (2006.01); A61B 3/107 (2006.01); A61B 3/135 (2006.01); A61F 9/007 (2006.01); A61K 49/00 (2006.01); A61B 3/14 (2006.01); A61F 9/008 (2006.01); A61N 5/067 (2006.01); A61M 37/00 (2006.01);
U.S. Cl.
CPC ...
A61M 5/007 (2013.01); A61B 3/10 (2013.01); A61B 3/107 (2013.01); A61B 3/135 (2013.01); A61B 3/145 (2013.01); A61B 5/0071 (2013.01); A61F 9/008 (2013.01); A61F 9/0079 (2013.01); A61K 49/006 (2013.01); A61N 5/062 (2013.01); A61B 5/0066 (2013.01); A61F 2009/00851 (2013.01); A61F 2009/00872 (2013.01); A61F 2009/00893 (2013.01); A61M 37/0092 (2013.01); A61N 2005/067 (2013.01); A61N 2005/0626 (2013.01); A61N 2005/0661 (2013.01);
Abstract

Devices and approaches for monitoring time based photo active agent delivery or photo active marker presence in an eye. A monitoring system is provided for measuring the presence of a photo active marker by illuminating the eye so as to excite the photo-active marker and then observing characteristic emission from the photo active marker. Example systems incorporate Scheimpflug optical systems or slit lamp optical systems to observe cross sectional images of an eye to monitor instantaneous distribution, diffusion pattern, and rate of uptake of a photo active agent applied to an eye. Systems and methods further allow for utilizing the monitored distribution of photo active agent in the eye as feedback for a cross-linking system.


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