The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2018
Filed:
Jan. 17, 2017
Applicant:
Korea University Research and Business Foundation, Seoul, KR;
Inventors:
Jae-Hong Seo, Gwacheon-si, KR;
Chang Ill Ban, Pohang-si, KR;
Hun-Ho Jo, Busan, KR;
Ji-Young Kim, Seoul, KR;
Young-Kwan Cho, Ansan-si, KR;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 47/55 (2017.01); A61K 47/48 (2006.01); C12N 15/115 (2010.01); A61K 31/5365 (2006.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
A61K 47/55 (2017.08); A61K 31/5365 (2013.01); A61K 47/48092 (2013.01); A61K 47/6855 (2017.08); C12N 15/115 (2013.01); C12N 2310/16 (2013.01); C12N 2310/351 (2013.01); C12N 2320/31 (2013.01);
Abstract
A method of manufacturing a complex for cancer cell chemotherapy comprises an aptamer preparation step of preparing a nucleic acid aptamer having an aptamer base sequence specifically binding to HER2, and a complex formation step of forming an aptamer-anticancer drug complex by reacting the aptamer prepared in the aptamer preparation step with an anticancer drug.