The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

Mar. 13, 2014
Applicant:

Takeda Vaccines, Inc., Cambridge, MA (US);

Inventors:

Dan T. Stinchcomb, Enumclaw, WA (US);

Jill A. Livengood, Fort Collins, CO (US);

Laszlo Varga, Fort Collins, CO (US);

Assignee:

Takeda Vaccines, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 39/12 (2006.01); A61K 47/22 (2006.01); A61K 47/26 (2006.01); A61K 47/42 (2017.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 47/22 (2013.01); A61K 47/26 (2013.01); A61K 47/42 (2013.01); A61K 2039/5254 (2013.01); C12N 2770/36134 (2013.01);
Abstract

Embodiments herein relate to compositions of and methods for live attenuated alphaviruses. In certain embodiments, a live, attenuated virus composition includes, but is not limited to, one or more live, attenuated alphaviruses and compositions to reduce inactivation and/or degradation of the live, attenuated alphavirus. In other embodiments, the live, attenuated virus composition may be a vaccine composition. In yet other compositions, a live, attenuated alphavirus composition may include HEPES buffer. In other embodiments, the HEPES buffer may further include a carbohydrate and gelatin and/or a salt.


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