The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2018
Filed:
Dec. 19, 2014
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Sara Belli, Oberrohrdorf, CH;
Konrad Bleicher, Freiburg, DE;
Richard D. Dimarchi, Carmel, IN (US);
Eike Hoffmann, Herrsching a. Ammersee, DE;
Eric A. Kitas, Aasch Baselland, CH;
Anish A. Konkar, North Bethesda, MD (US);
INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION, Indianapolis, IN (US);
HOFFMANN-LA ROCHE INC., Little Falls, NJ (US);
Abstract
Herein is reported a fusion polypeptide comprising i) one, two, three or four incretin receptor ligand polypeptides, and ii) one human immunoglobulin Fc-region, wherein at least one of the incretin receptor ligand polypeptides comprises an amino acid that is covalently conjugated to a lipid, and wherein each of the one, two, three or four incretin receptor ligand polypeptides is covalently conjugated by a peptide bond to a terminus of the human immunoglobulin Fc-region, whereby to each terminus of the human immunoglobulin Fc-region only a single incretin receptor ligand polypeptide is conjugated.