The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2018
Filed:
Jul. 14, 2014
The Board of Trustees of the University of Arkansas, Little Rock, AR (US);
Daohong Zhou, Little Rock, AR (US);
Yi Luo, Little Rock, AR (US);
Lijian Shao, Little Rock, AR (US);
Wei Feng, Little Rock, AR (US);
Jianhui Chang, Little Rock, AR (US);
Daohong Zhou, Little Rock, AR (US);
Yi Luo, Little Rock, AR (US);
Lijian Shao, Little Rock, AR (US);
Wei Feng, Little Rock, AR (US);
Jianhui Chang, Little Rock, AR (US);
BioVentures, LLC, Little Rock, AR (US);
Abstract
The invention generally features compositions and methods for expanding long term hematopoietic stem cells (HSCs) in a population of cells. In particular, the invention relates to a method of expanding long term HSCs by culturing an initial population of HSCs with macrophages that promote self-renewal of long term HSCs. The expanded cell population provides a source of cells for therapeutic treatments utilizing HSC transplantation.