The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 27, 2018
Filed:
Nov. 07, 2016
Applicant:
The Trustees of Columbia University IN the City of New York, New York, NY (US);
Inventors:
Samuel C. Silverstein, New York, NY (US);
John D. Loike, Jamaica, NY (US);
Sadna Budhu, Pelham, NY (US);
Peter Lee, Menlo Park, NY (US);
Assignee:
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); A61K 35/17 (2015.01); A61K 38/20 (2006.01); A61K 45/06 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 38/20 (2013.01); A61K 38/208 (2013.01); A61K 38/2013 (2013.01); A61K 45/06 (2013.01); G01N 33/5017 (2013.01); G01N 33/5047 (2013.01); A61K 2035/124 (2013.01); C12N 2503/00 (2013.01);
Abstract
A method is provided for treating a subject suffering from an infectious or neoplastic disease with immunotherapy. The method comprises determining the critical concentration of immune cells required to treat or eradicate an infectious or neoplastic disease in the subject using an in vitro assay of the present invention; and administering to the subject the critical concentration of immune cells determined in the assay.