The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

May. 18, 2018
Applicants:

Erica D. Bruce, Hewitt, TX (US);

John W. Woodmansee, Jr., Frisco, TX (US);

Inventors:

Erica D. Bruce, Hewitt, TX (US);

John W. Woodmansee, Jr., Frisco, TX (US);

Assignee:

BAYLOR UNIVERSITY, Waco, TX (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 33/08 (2006.01); A61K 9/08 (2006.01); A61K 47/02 (2006.01); A61K 9/00 (2006.01); A61K 33/06 (2006.01); A61K 47/69 (2017.01); A61K 47/52 (2017.01);
U.S. Cl.
CPC ...
A61K 33/08 (2013.01); A61K 9/0026 (2013.01); A61K 9/08 (2013.01); A61K 33/06 (2013.01); A61K 47/02 (2013.01); A61K 47/52 (2017.08); A61K 47/6921 (2017.08); A61K 47/6923 (2017.08);
Abstract

A method of treating a mammal, comprising administering a therapeutically effective amount of a poly-oxygenated metal hydroxide composition to a mammal to reduce a proliferation of hypoxic carcinoma cells, wherein the poly-oxygenated metal hydroxide composition comprises a clathrate containing free oxygen gas (O) molecules. The carcinoma cells may comprise colon adenocarcinoma cells (CaCo-2). The poly-oxygenated metal hydroxide material is configured to provide bioavailable oxygen gas molecules to a mammal when administered to the mammal. The poly-oxygenated metal hydroxide composition can be administered intravenously, directly to carcinoma cells, and orally. The composition may comprise a fluid, where the poly-oxygenated metal hydroxide composition is soluble in the fluid.


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