The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2018

Filed:

Oct. 21, 2015
Applicant:

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Inventors:

Hartmut Rehwinkel, Berlin, DE;

Sonja Anlauf, Wermelskirchen, DE;

Duy Nguyen, Berlin, DE;

Olaf Panknin, Berlin, DE;

Marcus Bauser, Berlin, DE;

Katja Zimmermann, Düsseldorf, DE;

Stefan Kaulfuss, Berlin, DE;

Roland Neuhaus, Berlin, DE;

Paul Matthew Blaney, Glossop, GB;

Gianna Toschi, Buxton, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 235/30 (2006.01); A61K 31/4184 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4184 (2013.01); C07D 235/30 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 413/04 (2013.01);
Abstract

The present invention relates to benzimidazol-2-amines of general formula (I) in which R, R, R, R, R, R, R, R, R, R, Rand Rare as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.


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