The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2018
Filed:
Nov. 27, 2013
Applicant:
Nektar Therapeutics, San Francisco, CA (US);
Inventors:
Yen Lin Chia, Los Gatos, CA (US);
Ute Hoch, San Francisco, CA (US);
Alison Hannah, Sebastopol, CA (US);
Michael A. Eldon, Redwood City, CA (US);
Assignee:
Nektar Therapeutics, San Francsico, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); A61K 31/4745 (2006.01); A61K 47/60 (2017.01);
U.S. Cl.
CPC ...
G01N 33/57415 (2013.01); A61K 31/4745 (2013.01); A61K 47/60 (2017.08); G01N 33/574 (2013.01); G01N 2333/4725 (2013.01); G01N 2333/705 (2013.01); G01N 2800/52 (2013.01);
Abstract
Provided is a method of treating an individual suffering from a cancer such as breast cancer by administering to the individual a long-acting topoisomerase I inhibitor such as SN-38 or irinotecan, and correlating the level of at least one tumor marker such as CA27.29 in the individual with response of the cancer to treatment with the long-acting topoisomerase I inhibitor, to thereby provide a method for predicting and assessing the therapeutic efficacy of the treatment.