The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2018
Filed:
Mar. 06, 2015
Kao Corporation, Chuo-ku, Tokyo, JP;
Kao Corporation, Tokyo, JP;
Abstract
A method for evaluating or selecting an agent for suppressing GIP level elevation, comprising the following steps (A) to (D): (A) contacting a test substance with a mammal-derived tissue or cell capable of expressing an FABP4 gene or FABP5 gene, or an FABP4 protein or FABP5 protein; (B) measuring an expression level of the FABP4 gene or FABP5 gene, an expression level of the FABP4 protein or FABP5 protein, or an activity of the FABP4 protein or FABP5 protein in the mammal-derived tissue or cell; (C) comparing the expression level or activity measured in the above (B) with an expression level of an FABP4 gene or FABP5 gene, an expression level of an FABP4 protein or FABP5 protein, or an activity of an FABP4 protein or FABP5 protein in a control group; and (D) evaluating or selecting a test substance which reduces the expression level of the FABP4 gene or FABP5 gene, the expression level of the FABP4 protein or FABP5 protein, or the activity of the FABP4 protein or FABP5 protein as an agent suppressing GIP level elevation based on results of the above (C).