The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2018

Filed:

Jun. 26, 2017
Applicant:

Foce Technology International Bv, Maria Hoop, NL;

Inventors:

Thomas Obrien, Eindhoven, NL;

Hendrik Dijkstra, Eindhoven, NL;

Marcel F Schemmann, Maria Hoop, NL;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 15/14 (2006.01); G02B 27/00 (2006.01); G06K 9/52 (2006.01); G06K 9/00 (2006.01); G06K 9/78 (2006.01); G02B 21/36 (2006.01); G02B 21/06 (2006.01); G01N 15/00 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
G01N 15/1463 (2013.01); G01N 15/1434 (2013.01); G01N 15/1475 (2013.01); G02B 21/06 (2013.01); G02B 21/365 (2013.01); G02B 21/367 (2013.01); G02B 27/0025 (2013.01); G06K 9/00134 (2013.01); G06K 9/52 (2013.01); G06K 9/78 (2013.01); G01N 2015/0065 (2013.01); G01N 2015/0084 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1445 (2013.01); G01N 2015/1452 (2013.01); G01N 2015/1486 (2013.01);
Abstract

Platelets or blood cells are detected in a fluid sample by adjusting a focal depth of a microscope through a range of values, the microscope having a mounted sample and an objective lens adapted with one or both of (a) a spherical aberration correction unmatched to a utilized cover plate for the sample, or (2) a numerical aperture unmatched to a utilized illumination source for the sample. Images are recorded at different specific focal depths and in multiple z planes of a fluid bearing the platelets, where the position of platelets may overlap on different of the multiple z planes that are recorded, the images recorded through the cover plate, thus causing the generation of a specific light-dark pattern indicative of platelets at particular positions and at multiple depths in the fluid media. The images are analyzed for the specific light-dark pattern.


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