The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2018

Filed:

Mar. 13, 2014
Applicant:

Takara Bio Inc., Shiga, JP;

Inventors:

Kiyoyuki Matsumura, Otsu, JP;

Nariaki Takatsu, Kusatsu, JP;

Takashi Uemori, Otsu, JP;

Hiroyuki Mukai, Beijing, CN;

Assignee:

TAKARA BIO INC., Shiga, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12P 19/34 (2006.01); C12Q 1/68 (2018.01); C12Q 1/683 (2018.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); C12P 19/34 (2013.01); C12Q 1/683 (2013.01); C12Y 301/21 (2013.01);
Abstract

Provided are a mismatch-specific cleavage reaction using a novel heat-resistant mismatch nuclease, a method for removing errors in a nucleic acid amplification reaction using the mismatch nuclease, a method for inhibiting the amplification of a nucleic acid having a specific base sequence during a nucleic acid amplification reaction, and a method for detecting a nucleic acid having a single-base polymorphic mutation using this inhibition method.


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