The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2018

Filed:

Sep. 12, 2016
Applicant:

General Electric Company, Schenectady, NY (US);

Inventors:

Reginald Donovan Smith, Schenectady, NY (US);

Prameela Susarla, Manvel, TX (US);

Slawomir Rubinsztajn, Ballston Spa, NY (US);

Brian David Polizzotti, Swampscott, MA (US);

Anton Beletskii, Niskayuna, NY (US);

Assignee:

GENERAL ELECTRIC COMPANY, Schenectady, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C08F 293/00 (2006.01); C12M 1/26 (2006.01); C12M 1/00 (2006.01); C08F 8/12 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0075 (2013.01); C08F 8/12 (2013.01); C08F 293/005 (2013.01); C12M 23/20 (2013.01); C12M 33/00 (2013.01); C12N 5/0068 (2013.01); C12N 2533/30 (2013.01); C12N 2539/10 (2013.01);
Abstract

A cell culture support comprising a substrate, and a dual stimuli responsive block copolymer immobilized on the substrate, wherein the dual stimuli responsive block copolymer is both thermoresponsive and pH responsive. A method of culturing cells comprising the cell culture support having a dual stimuli responsive copolymer immobilized on a substrate, wherein the dual stimuli responsive copolymer is thermoresponsive and pH responsive; and growing the cells on the cell culture support. By lowering the temperature, cells are released from the cell culture support.


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