The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2018

Filed:

Sep. 08, 2017
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Anthony Estrada, San Carlos, CA (US);

Snahel Patel, Foster City, CA (US);

Terry Kellar, Burlingame, CA (US);

Malcolm Huestis, San Francisco, CA (US);

Daniel Shore, San Francisco, CA (US);

Michael Siu, Burlingame, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/14 (2006.01); C07D 491/14 (2006.01); C07D 519/00 (2006.01); A61K 31/5383 (2006.01); A61K 45/06 (2006.01); A61K 31/553 (2006.01);
U.S. Cl.
CPC ...
C07D 498/14 (2013.01); A61K 31/5383 (2013.01); A61K 31/553 (2013.01); A61K 45/06 (2013.01); C07D 491/14 (2013.01); C07D 519/00 (2013.01);
Abstract

The invention relates to compounds of formula (I) and salts thereof: wherein ring A and R-Rhave any of the values defined in the specification. The compounds and salts are useful for treating DLK mediated disorders. The invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable salt thereof, as well as methods of using said compounds, salts, or compositions as DLK inhibitors and for treating neurodegeneration diseases and disorders.


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