The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2018
Filed:
Aug. 26, 2015
Applicant:
Sunnylife Pharma, Inc., Indianapolis, IN (US);
Inventors:
Jonathan A. Groeper, Greenwood, IN (US);
Xibin Liao, Edison, NJ (US);
Zhijian Lu, Plainfield, IN (US);
Assignee:
Sunnylife Pharma, Inc., Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61P 3/04 (2006.01); A61P 13/10 (2006.01); A61P 25/18 (2006.01); A61P 25/24 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 3/04 (2018.01); A61P 3/10 (2018.01); A61P 13/10 (2018.01); A61P 25/18 (2018.01); A61P 25/24 (2018.01);
Abstract
Certain tetrahydro-azepinoquinolines of structural formula I are agonists of the mammalian 5-HTreceptor, and, in particular, are selective agonists of the mammalian 5-HTreceptor. The compounds of the present invention are therefore useful for the treatment, control, or prevention of diseases, conditions, or disorders responsive to stimulation of the 5-HTreceptor, such as obesity, obesity-related conditions, and certain CNS-related disorders, including schizophrenia and depression. They are also useful as aids for tobacco smoking cessation.