The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2018
Filed:
Jan. 31, 2014
Applicant:
Alumend, Llc, Sioux Falls, SD (US);
Inventors:
Barbara R. Haberer, Hartford, SD (US);
Therese J. Downey, Sioux Falls, SD (US);
Ronald E. Utecht, Volga, SD (US);
Jeffrey E. Elbert, Waterloo, IA (US);
Assignee:
Alumend, LLC, Sioux Falls, SD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 221/14 (2006.01); C07D 405/14 (2006.01); C07D 498/18 (2006.01); C07D 498/22 (2006.01); A61K 31/473 (2006.01); A61K 31/4985 (2006.01); A61K 41/00 (2006.01); A61M 25/10 (2013.01); A61N 5/06 (2006.01); A61K 47/54 (2017.01); A61N 5/067 (2006.01);
U.S. Cl.
CPC ...
C07D 221/14 (2013.01); A61K 31/473 (2013.01); A61K 31/4985 (2013.01); A61K 41/0042 (2013.01); A61K 47/545 (2017.08); A61M 25/104 (2013.01); A61N 5/062 (2013.01); C07D 405/14 (2013.01); C07D 498/18 (2013.01); C07D 498/22 (2013.01); A61N 2005/067 (2013.01); Y02A 50/406 (2018.01);
Abstract
Disclosed herein is a compound for use in a composition applied to a blood vessel, wherein the compound softens and/or disrupts the crystalline matrix of calcified plaque. Methods of treatment comprising applying the disclosed composition are also disclosed. Plaque-softening compounds are also disclosed.