The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2018

Filed:

Jun. 02, 2017
Applicant:

Thetis Pharmaceuticals Llc, Branford, CT (US);

Inventors:

Frank C. Sciavolino, Waterford, CT (US);

Gary Mathias, Ridgefield, CT (US);

Michael C. Van Zandt, Guilford, CT (US);

Gunnar Erik Jagdmann, Jr., Branford, CT (US);

Jessica J. Dworak, Middletown, CT (US);

Assignee:

Thetis Pharmaceuticals LLC, Branford, CT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2017.01); A61K 31/202 (2006.01); A61K 31/232 (2006.01); A61K 47/62 (2017.01); A61P 1/06 (2006.01); A61P 1/12 (2006.01); A61P 1/04 (2006.01); A61P 1/00 (2006.01); A61P 29/00 (2006.01); A61K 38/03 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 47/541 (2017.08); A61K 31/202 (2013.01); A61K 31/232 (2013.01); A61K 38/03 (2013.01); A61K 45/06 (2013.01); A61K 47/62 (2017.08); A61P 1/00 (2018.01); A61P 1/04 (2018.01); A61P 1/06 (2018.01); A61P 1/12 (2018.01); A61P 29/00 (2018.01); A61K 2800/00 (2013.01);
Abstract

The present invention relates to compounds which are salts of specialized pro-resolving mediators (referred to herein as 'SPMs') which include lipoxins, resolvins, protectins, and their aspirin-triggered counterparts. The SPM salts described here contain at least one or two SPM molecules ionically bound to at least one basic function that is provided by a scaffold moiety as described herein, compositions containing same, and methods of using same in the treatment of various diseases and disorders characterized by chronic or excessive inflammation, or both.


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