The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2018
Filed:
Aug. 18, 2017
Vedanta Biosciences, Inc., Cambridge, MA (US);
Riken, Wako-shi, Saitama, JP;
Kenya Honda, Yokohama, JP;
Bernat Olle, Cambridge, MA (US);
Koji Atarashi, Yokohama, JP;
Takeshi Tanoue, Yokohama, JP;
Hiroshi Ohno, Yokohama, JP;
Shinji Fukuda, Yokohama, JP;
Koji Hase, Yokohama, JP;
Vedanta Biosciences, Inc., Cambridge, MA (US);
RIKEN, Wako-shi, Saitama, JP;
Abstract
Compositions consisting of bioactive molecules derived from the microbiota of a mammal are provided herein. When administered orally with a colonic delivery system, the compositions are useful for the prophylaxis and treatment of diseases, in particular inflammatory, autoimmune and infectious diseases. The compositions comprise combinations of small molecules and bacterial antigens formulated in colonic delivery systems. Use of the compositions results in any or all of: induction of immune tolerance; strengthening of the gut mucosal barrier integrity; reduction of inflammation; and amelioration of a disease state caused by inflammation, an autoimmune reaction or an infectious agent.