The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2018
Filed:
Dec. 29, 2015
Applicant:
Bioventus, Llc, Durham, NC (US);
Inventors:
Eric Vanderploeg, Stoneham, MA (US);
Howard Seeherman, Cambridge, MA (US);
Christopher G. Wilson, Auburndale, MA (US);
John Wozney, Hudson, MA (US);
Christopher T. Brown, Chelmsford, MA (US);
John A. Kambouris, Durham, NC (US);
Assignee:
Bioventus, LLC., Durham, NC (US);
Primary Examiner:
Int. Cl.
CPC ...
A61L 24/00 (2006.01); A61L 27/12 (2006.01); A61K 38/17 (2006.01); A61K 33/06 (2006.01); A61L 27/44 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61K 38/18 (2006.01); A61L 24/02 (2006.01);
U.S. Cl.
CPC ...
A61K 38/17 (2013.01); A61K 33/06 (2013.01); A61K 38/1875 (2013.01); A61L 24/0015 (2013.01); A61L 24/0036 (2013.01); A61L 24/0084 (2013.01); A61L 24/02 (2013.01); A61L 27/12 (2013.01); A61L 27/446 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 2300/414 (2013.01); A61L 2430/02 (2013.01); A61L 2430/38 (2013.01);
Abstract
Systems and methods for preparing synthetic osteoinductive bone grafts are provided in which a porous ceramic granule, which may be incorporated within a biocompatible matrix material, is loaded with an osteoinductive agent. Loading of granules is facilitated in some cases by the use of low-pH buffers and pre-treatments.