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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10130667 B1

PDFFull Text
Expired
Date of Patent:
Nov. 20, 2018

Filed:

Apr. 15, 2016

Taa/ecdcd40l oncolytic virus

Applicant:

Albert B. Deisseroth, Potomac, MD (US);

Inventor:

Albert B. Deisseroth, Potomac, MD (US);

Assignee:

MicroVAX, LLC, Warrenton, VA (US);

Attorneys:

Jacob Frank

Glenn Snyder

Primary Examiner:

Rachel B Gill

Int. Cl.
CPC ...
A61K 35/761 (2015.01); A61K 48/00 (2006.01); C12N 7/00 (2006.01); A61K 38/16 (2006.01); A61K 9/00 (2006.01); A61K 31/513 (2006.01); A61K 38/50 (2006.01); A61K 39/00 (2006.01); C12N 15/861 (2006.01); C07K 14/005 (2006.01);
U.S. Cl.
CPC ...
A61K 35/761 (2013.01); A61K 9/0019 (2013.01); A61K 31/513 (2013.01); A61K 38/162 (2013.01); A61K 38/50 (2013.01); A61K 39/0011 (2013.01); A61K 48/0058 (2013.01); C12N 7/00 (2013.01); A61K 2039/53 (2013.01); C07K 14/005 (2013.01); C12N 15/861 (2013.01); C12N 2710/00011 (2013.01); C12N 2710/10011 (2013.01); C12N 2710/10032 (2013.01); C12N 2710/10034 (2013.01); C12N 2710/10041 (2013.01); C12N 2710/10332 (2013.01); C12N 2710/10343 (2013.01); C12Y 305/04001 (2013.01);
Abstract

The present invention relates to a vaccine comprising the insertion of three genes, the TAA/ecdCD40L EA1 and CDA, driven by promoters L-plastin/cytosinedeaminase and CMV as a three gene, three transcription unit oncolytic virus as a conditionally replication competent adenoviral vector which replicates only in tumor cells. In these transcription units, the E1A gene of the adenoviral vector as well as the cytosine deaminase gene are under the control of the L-plastin promoter, while the TAA/ecdCD40L transcription unit is under control of a the CMV promoter.

Find Patent Forward Citations

Deisseroth, Albert. (2018). Taa/ecdcd40l oncolytic virus (U.S. Patent No. 10130667). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10130667

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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