The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2018
Filed:
Nov. 04, 2013
Applicant:
Duke University, Durham, NC (US);
Inventors:
Victor J. Dzau, Durham, NC (US);
Maria Mirotsou, Durham, NC (US);
Assignee:
DUKE UNIVERSITY, Durham, NC (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/551 (2006.01); A61K 31/437 (2006.01); A61K 45/06 (2006.01); C07D 487/04 (2006.01); C07D 401/14 (2006.01); C12N 15/113 (2010.01); A61K 35/34 (2015.01);
U.S. Cl.
CPC ...
A61K 31/551 (2013.01); A61K 31/437 (2013.01); A61K 35/34 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 487/04 (2013.01); C12N 15/1137 (2013.01); C12Y 201/01043 (2013.01); C12Y 201/01125 (2013.01); C12Y 207/10002 (2013.01); C12Y 207/11001 (2013.01); C12N 2310/141 (2013.01); C12N 2320/30 (2013.01);
Abstract
A method for promoting the reprogramming of a non-cardiomyocytic cell or tissue into cardiomyocytic cell or tissue comprising is carried out by contacting a non-cardiomyocytic cell or tissue with a modulator of histone methyltransferase activity or expression.