The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2018

Filed:

Apr. 06, 2017
Applicants:

Unity Biotechnology, Inc., Brisbane, CA (US);

Buck Institute for Research on Aging, Novato, CA (US);

The Johns Hopkins University, Baltimore, MD (US);

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

Nathaniel David, San Francisco, CA (US);

Albert Davalos, San Rafael, CA (US);

Remi-Martin Laberge, San Francisco, CA (US);

Judith Campisi, Berkeley, CA (US);

Marco Demaria, Groningen, NL;

Alain Vasserot, Carlsbad, CA (US);

Chaekyu Kim, Pikesville, MD (US);

Okhee Jeon, Baltimore, MD (US);

Jennifer Elisseeff, Baltimore, MD (US);

James L. Kirkland, Rochester, MN (US);

Tamar Tchkonia, Rochester, MN (US);

Yi Zhu, Rochester, MN (US);

Assignees:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/495 (2006.01); A61K 31/404 (2006.01); A61K 31/4375 (2006.01); A61K 31/428 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); A61K 31/4178 (2006.01); A61K 31/728 (2006.01); C12N 5/00 (2006.01); A61K 47/36 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 9/0048 (2013.01); A61K 9/0073 (2013.01); A61K 31/404 (2013.01); A61K 31/4178 (2013.01); A61K 31/428 (2013.01); A61K 31/4375 (2013.01); A61K 31/495 (2013.01); A61K 31/5377 (2013.01); A61K 31/728 (2013.01); A61K 45/06 (2013.01); A61K 47/36 (2013.01); C12N 5/0081 (2013.01); C12N 2501/999 (2013.01); C12N 2503/02 (2013.01);
Abstract

This disclosure provides a technology for managing the sensation of pain in a subject in need thereof. Treatment methods according to this invention include administering to the subject a formulation that contains an effective amount of (4-[(4S,5R)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone).


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