The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2018
Filed:
May. 07, 2012
Sunghoon Kim, Seoul, KR;
Jin Woo Choi, Seoul, KR;
Jin Young Lee, Seoul, KR;
Dae Gyu Kim, Seoul, KR;
Gyoon Hee Han, Hwaseong-si, KR;
Jee Sun Yang, Seoul, KR;
Chul Ho Lee, Seoul, KR;
Sunghoon Kim, Seoul, KR;
Jin Woo Choi, Seoul, KR;
Jin Young Lee, Seoul, KR;
Dae Gyu Kim, Seoul, KR;
Gyoon Hee Han, Hwaseong-si, KR;
Jee Sun Yang, Seoul, KR;
Chul Ho Lee, Seoul, KR;
Abstract
This application relates to a novel benzo-heterocycle derivative and more particularly, it relates a composition for preventing and treating cancer or for inhibiting metastasis comprising benzo-heterocycle derivative or pharmaceutically acceptable salts thereof as an active ingredient. The present inventors confirmed that KRS has an effect on cancer metastasis by facilitating cancer (or tumor) cell migration through interaction with 67LR, and also found that a substance inhibiting the interaction between KRS and 67LR can prevent and treat cancer by inhibiting cancer cell metastasis. Accordingly, the composition of the present invention can inhibit cancer metastasis, and thus provide a novel means for prevention and treatment of cancer.