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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10130588 B1

PDFFull Text
Date of Patent:
Nov. 20, 2018

Filed:

Dec. 12, 2012

Functionalised silicon nanoparticles

Applicants:

Westfaelische Wilhelms-universitaet Muenster, Muenster, DE;

Helmholtz-zentrum Dresden-rossendorf, Dresden, DE;

Inventors:

Holger Stephan, Dresden, DE;

Ralf Bergmann, Dresden, DE;

Alexander Ruffani, Heidenau, DE;

Luisa DeCola, Strasbourg, FR;

Assignee:

WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER, Munich, DE;

Attorneys:

24IP Law Group

Timothy R DeWitt

Primary Examiner:

Robert S Cabral

Int. Cl.
CPC ...
A61K 9/51 (2006.01); C01B 33/02 (2006.01); C09C 1/28 (2006.01); C09C 1/30 (2006.01); C01B 33/027 (2006.01); A61K 49/00 (2006.01); A61K 51/12 (2006.01); B82Y 30/00 (2011.01); A61K 31/282 (2006.01); A61K 31/337 (2006.01); A61K 31/513 (2006.01); A61K 31/519 (2006.01); A61K 31/65 (2006.01); A61K 33/24 (2006.01); C07F 7/08 (2006.01); A61K 47/54 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 9/5123 (2013.01); A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/513 (2013.01); A61K 31/519 (2013.01); A61K 31/65 (2013.01); A61K 33/24 (2013.01); A61K 47/54 (2017.08); A61K 47/6923 (2017.08); A61K 49/0093 (2013.01); A61K 51/1244 (2013.01); B82Y 30/00 (2013.01); C01B 33/02 (2013.01); C01B 33/027 (2013.01); C07F 7/0827 (2013.01); C09C 1/28 (2013.01); C09C 1/3063 (2013.01); C01P 2002/82 (2013.01); C01P 2002/84 (2013.01); C01P 2004/04 (2013.01); C01P 2004/64 (2013.01); C01P 2004/84 (2013.01); C01P 2006/42 (2013.01); Y10T 428/2982 (2015.01);
Abstract

The present invention is related to silicon nanoparticles, a pharmaceutical composition comprising silicon nanoparticles, a method for synthesis of the silicon nanoparticles and their use for in vivo diagnostics, visualization of drug delivery or staining of cells, biological processes or pathways. The silicon nanoparticles are characterized that they comprise a silicon core of a size of 1 to 10 nm and are terminated with allylamine or poly(allylamine) comprising up to 10 allylamine groups.

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