The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 13, 2018

Filed:

Jan. 13, 2015
Applicant:

Proteros Biostructures Gmbh, Martinsried, DE;

Inventors:

Adrian Schomburg, Gräfelfing, DE;

Robert Van Der Burgh, Munich, DE;

Assignee:

PROTEROS BIOSTRUCTURES GMBH, Martinsried, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/542 (2006.01); G01N 33/68 (2006.01); G01N 33/573 (2006.01); G01N 33/58 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6875 (2013.01); G01N 21/6428 (2013.01); G01N 33/542 (2013.01); G01N 33/573 (2013.01); G01N 33/582 (2013.01); G01N 2021/6432 (2013.01);
Abstract

The present invention relates to methods for determining a binding and/or functional interaction of a protein of interest with a nucleosomal substrate wherein at least one of the histone types of the nucleosomal substrate has a homogenous post-translational modification pattern. Further, the invention relates to nucleosomal substrates, wherein at least one of the histone types of the nucleosomal substrate has a homogenous post-translational modification pattern, and to methods for providing such nucleosomal substrates.


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