The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 13, 2018

Filed:

Jul. 24, 2013
Applicant:

University of Vermont and State Agricultural College, Burlington, VT (US);

Inventors:

Christopher Francklyn, Burlington, VT (US);

Karen M. Lounsbury, Essex Junction, VT (US);

Jason Botten, Williston, VT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/43 (2006.01); A61K 45/06 (2006.01); C12N 9/00 (2006.01); A61K 38/53 (2006.01); G01N 33/50 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/93 (2013.01); A61K 38/43 (2013.01); A61K 38/53 (2013.01); A61K 45/06 (2013.01); G01N 33/5064 (2013.01); A61K 48/00 (2013.01); C12Y 601/01003 (2013.01); G01N 2333/82 (2013.01); G01N 2333/9015 (2013.01); G01N 2500/02 (2013.01);
Abstract

The invention includes, in part, methods and compounds for treating diseases and conditions characterized by reduced threonyl-tRNA synthetase (TARS) activity, which include, but are not limited to diseases and conditions in which angiogenesis is reduced as compared to normal. In some embodiments of the invention, a level of a TARS molecule is determined and compared to a control level of TARS to assess a treatment for a disease or condition characterized by reduced TARS activity.


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